Page 1 of 2
Rajiv Gandhi University of Health Sciences, Karnataka
Fourth Semester B. Pharm Degree Examination – 16-Jan-2020
Time: Three Hours Max. Marks: 75 Marks
PHARMACOLOGY - I
Q.P. CODE: 5016
Your answers should be specific to the questions asked.
Draw neat labeled diagrams wherever necessary.
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
1. What are types of receptors? Explain in detail G-protein coupled receptors and ion channel
receptor. (3+7)
2. What are parasympathomimetics? Classify parasympathomimetics. Explain in detail any one
parasympathomimetics. (1+2+7)
3. What is epilepsy? Classify anti-epileptics. Explain in detail pharmacology of phenytoin. (1+2+7)
SHORT ESSAYS (Answer any Seven) 7 x 5 = 35 Marks
4. Explain different nature and source of drugs with examples.
5. Classify route of drug administration. Explain merits and demerit of parenteral routes of drug
administration.
6. What are drug interactions? Explain in detail pharmacokinetic drug interactions.
7. Explain in detail about clinical trials.
8. Classify neuromuscular blocking agents. Add a note on any one agent.
9. Explain neurohumaral transmission with note on co-transmission.
10. Explain in detail stages of general anesthesia.
11. Short note on CNS stimulants.
12. Explain in detail opioid analgesics.
SHORT ANSWERS (Answer All) 10 x 2 = 20 Marks
13. What is drug addiction and drug dependence?
14. Write merits and demerits of rectal routes of drug administration.
15. What are pharmacodynamic drug interactions? Give examples.
16. What is Pharmacovigilance?
17. Write the classification of antidepressants with examples.
18. Enlist drugs used in treatment of myasthenia gravis and glaucoma.
19. Write about Disulfiram.
20. Drugs used in Antipsychotics.
21. Enlist the drugs used in Parkinsons disease.
22. Give the examples of short acting barbiturates with their uses.
*****
Page 2 of 2
Rajiv Gandhi University of Health Sciences, Karnataka
Fourth Semester B. Pharm Degree Examination – JUNE-2019
Time: Three Hours Max. Marks: 75 Marks
Pharmacology - I
Q.P. CODE: 5016
Your answers should be specific to the questions asked
Draw neat labeled diagrams wherever necessary
LONG ESSAYS (Answer any Two) 2 x 10 = 20 Marks
1. Explain about different routes of drug administration.
2. Write the principle and mechanism of drug action.
3. Describe the neurohumoral transmission with examples.
SHORT ESSAYS (Answer any Seven) 7 x 5 = 35 Marks
4. What do you mean by competitive antagonism?
5. Explain the JAK-STAT binding receptor transduction mechanism.
6. What are the factors affecting the absorption of drugs?
7. Explain the pharmacology of MAO inhibitors.
8. Explain the organization of the autonomic nervous system.
9. Write the mechanism of action and pharmacology of sodium valproate.
10. Write the pharmacology of gabapentin.
11. Write brief notes on antagonistic drugs of morphine.
12. What is the role of serotonin in central nervous system?
SHORT ANSWERS (Answer All) 10 x 2 = 20 Marks
13. What are the different types of signal transduction mechanism?
14. What do you mean by drug receptor interactions?
15. What is the significance of therapeutic index?
16. What are the combined effects of drugs?
17. Enlist the neurotransmitters in Central Nervous System.
18. How the sympathomimetic agents are classified?
19. What are the adverse reactions of barbiturates?
20. Classify the muscle relaxants with examples.
21. Define the drug tolerance.
22. What are the withdrawal symptoms of anti-depressants?
*****